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Learning Objectives: Upon completion of this activity, participants will: Have increased knowledge regarding the Pathophysiologic mechanisms associated with GLP-1 RA/incretin-associated constipation Current evidence on the use of OTC treatments for managing GLP-1 RA/incretin-associated constipation Have greater competence related to Designing strategies to help manage GLP-1 RA/incretin-associated constipation SEGMENT 1: The Rising Use of GLP-1 RA/Incretin Therapies What Do Current Epidemiologic Data Show About the Rapid Expansion of GLP-1 RA/Incretin Use